
Technical Details |
Structure |
|
Chemical Name |
3, 3’, 5,5’, 6-pentachloro - 2’ - hydroxy - salicylanilide |
|
Molecular Formula |
C13H6Cl5NO3 |
|
Molecular Weight |
401.46 |
|
CAS No. |
2277-92-1 |
|
Action and use |
Anthelmintic (Flukicide) |
|
Preparation |
Oxyclozanide Oral Suspension |
|
Content |
99.0 per cent to 101.0 per cent (dried substance). |
|
Reference |
BP-2009 |
Sr. No. |
Test |
Specification |
1. |
Description |
Pale cream to cream-coloured powder |
2. |
Solubility |
Freely soluble in acetone; soluble in ethanol (95%); slightly soluble in dichloromethane; very slightly soluble in water |
3. |
Identification |
A: The IR absorption spectrum, Appendix II A, is concordant with the reference spectrum of Oxyclozanide (RSV 33) |
4. |
Ionisable Chloride |
Not more than 1.4 ml is required (0.25%) in 2 gm |
5. |
Related substance by HPLC |
i) Total Impurities before principle peak is Not more than 0.3% |
ii) Total impurities after principle peak is not more than 1.0% |
||
6. |
Sulphated Ash |
Not more than 0.2% |
7. |
Loss on Drying |
Not more than 1.0% |
8 |
Assay on dried basis, w/w |
It should be not less than 98.0% and not more than 101.0 % |